Jose G Assouline,Brian G. Trewyn,Sean K Sweeney,Kapil Kandel
申请号：
US14400518
公开号：
US20150125398A1
申请日:
2013.03.13
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention provides particles useful for sequential imaging or for diagnostics or therapeutics. Disclosed is a method to image diagnostic or therapeutic cells in a mammal, comprising: introducing to a mammal a composition comprising mammalian cells comprising mesoporous silica nanoparticles (MSNs) comprising a lanthanide, a fluorophore and an agent detectable by ultrasound applying ultrasound and/or a magnetic field to the mammal and recording ultrasound and/or magnetic resonance images that include the MSNs and detecting the presence, location or amount of the MSNs in the mammal.
