The present disclosure relates generally to methods of treating gonorrhea infections using quinolone antibiotics. In one aspect, methods of treating a Neisseria gonococcus infection in a patient in need thereof, the method comprising administering a therapeutically effective amount of an antibiotic compound otherwise contraindicated for treating said infection are disclosed herein. In another aspect, methods are disclosed herein of treating a Neisseria gonococcus infection in a patient in need thereof, the method comprising administering a therapeutically effective amount of delafloxacin or a pharmaceutically acceptable salt, ester, prodrug, polymorph or solvate thereof.La présente invention concerne, dune manière générale, des méthodes de traitement dinfections de gonorrhée au moyen dantibiotiques de quinolone.