The invention provides for an integrated device for forming a cavity in a surface of a tissue of an animal comprising:a) a controller board connected to an energy source for actuating at least one poratorb) a fluid reservoir in fluid communication with the tissue andc) a tissue interface layer, the tissue interface layer containing the at least one porator, the porator in contact with the tissue for forming the cavity.The invention also provides for methods of making and methods of using the same.