Polynucleotide, polypeptide with immunosuppressive activity, expression cassette, expression vector, host cell, pharmaceutical composition, methods for producing a polypeptide with immunosuppressive activity and for preventing or treating conditions that require immunosuppression, and use of a polypeptide
Denise V. Tambourgi,Giselle Pidde Queiroz,Osvaldo Augusto Brazil Esteves Sant'Anna,Fábio Carlos Magnoli,Ogari de Castro Pacheco,Osvaldo Augusto Brazil Esteves SantAnna
申请号：
US15031936
公开号：
US10081660B2
申请日:
2014.10.24
申请国别(地区):
US
年份:
2018
代理人:
摘要：
This invention refers to polynucleotides and non-hemorrhagic and non-immunogenic polypeptides of selective immunosuppressive activity on production of antibodies to antigens of different natures. The polypeptides described herein are useful for preparing pharmaceutical compositions for prevention or treatment of conditions that require immunosuppression, preferably, inflammatory, autoimmune, allergic and infectious diseases and rejection to transplanted organs.
