PROBLEM TO BE SOLVED: To provide a novel method for producing an optically active imidazole compound useful as a pharmaceutical.SOLUTION: A production method includes the steps for making a compound represented by formula (3) react with hydrogen gas in the presence of an optically active metal complex catalyst, to obtain a compound represented by formula (4) with high yield and high selectivity (in the formula, R1 is an amino protecting group, and * is an asymmetric carbon atom).SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】 本発明は、医薬品として有用な光学活性イミダゾール化合物の新規な製造方法を提供することを課題とする。【解決手段】 式(3)で表される化合物に、光学活性金属錯体触媒存在下、水素ガスを反応させることにより、高収率、高選択性で、式(4)で表される化合物を得る製造方法。【化1】(式中R1はアミノ保護基を表し、*は不斉炭素原子を表す。)【選択図】なし
