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FORMES POLYMORPHES DE CHLORHYDRATE DE 1-¬4-(5-CYANOINDOL-3-YL)BUTYL-4-(2-CARBAMOYLBENZOFURAN-5-YL)PIPERAZI NE
专利权人:
MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG
发明人:
BATHE, ANDREAS,HELFERT, BERND,NEUENFELD, STEFFEN,KNIEL, HEIKE,BARTELS, MATTHIAS,RUDOLPH, SUSANNE,BOTTCHER, HENNING
申请号:
CA2451028
公开号:
CA2451028C
申请日:
2002.06.05
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention relates to new crystalline modifications of the hydrochloride of1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine,crystalline modification of the dihydrochloride of 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine and amorphous 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazinehydrochloride which are suitable in particular for the preparation of solidmedicaments for the treatment or prevention of depressive disorders, anxietydisorders, bipolar disorders, mania, dementia, substance-related disorders,sexual dysfunctions, eating disorders, obesity, fibromyalgia, sleepingdisorders, psychiatric disorders, cerebral infarct, tension, for the therapyof side-effects in the treatment of hypogonadism, secondary amenorrhea,premenstrual syndrome and undesired puerperal lactation.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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