An infusion set comprising a base and a cap. The base can comprise a portion to be placed against skin, a first cannula extending downwardly below the portion to be placed against skin, and a septum. The cap can comprise a tube and a second cannula. The cap can be configured for removable attachment to the base such that the cap is rotatable with respect to the base while the first cannula, the second cannula, and the tube are in fluid communication.