The invention relates to medical uses of an HDAC inhibitor of the below general formula I, wherein R1 to R7 are as described herein, or a salt or solvate thereof in combination with LAG-3 inhibitor and a PD-1 inhibitor or PD-L1 inhibitor for the treatment of cancer.本發明涉及以下通式I之HDAC抑制劑、或其鹽或溶劑化物與LAG-3抑制劑和PD-1抑制劑或PD-L1抑制劑組合用於治療癌症的醫學用途,其中R1至R7如本文所述。