The present invention discloses anti-PD-L/PD-1 Axis antibody conjugates for targeted immunotherapy, as well as compositions comprising said conjugates. Further, the present invention discloses the use of the conjugates in the treatment of tumor/cancer.Cette invention concerne des conjugués danticorps anti-axe PD-L/PD-1 pour limmunothérapie ciblée, ainsi que des compositions les comprenant. Lutilisation desdits conjugués dans le traitement des tumeurs/cancers est en outre décrite.