A biodegradable and flushable film is generally provided. The film can be a multi-layer film including a water-dispersible core layer that comprises a water- soluble polymer; and a water-barrier skin layer positioned adjacent to the water- dispersible core layer. The water-dispersible core layer constitutes from about 50 wt.% to about 99 wt.% of the film, while the water-barrier skin layer constitutes from about 1 wt.% to about 50 wt.% of the film. The biodegradable polymers of the water-barrier skin layer can constitute from about 80 wt.% to 100 wt.% of the polymer content in the water-barrier skin layer, with from about 10 wt.% to about 90 wt.% of the biodegradable polymers being polyalkylene carbonate and from about 10 wt.% to about 90 wt.% of the biodegradable polymers being biodegradable polyesters. The film may be used as a packaging film or as a backsheet of an absorbent article.