Fluoro-substituted (3R, 4R, 5S)-5-guanidino-4-acylamino-3-(pentan-3-yloxy) cyclohexene-1-carboxylic acids, esters thereof and a method for the use thereof

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专利权人:

Asavi, LLC;Alexandre Ivachtchenko

发明人:

Ivachtchenko, Alexandre Vasilevich

申请号：

AU2013263513

公开号：

AU2013263513A1

申请日:

2013.05.07

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

The invention relates to novel inhibitors of neuraminidase activity and the use thereof for the prophylaxis and treatment of influenza infections, and specifically to fluoro-substituted 4-acylamino-5-guanidino-3-(pentan-3-yloxy) cyclohexene-1-carboxylic acids and esters thereof of general formula 1, and pharmaceutically acceptable salts and/or hydrates thereof, where R is hydrogen, optionally substituted by C

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