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MODULATEURS À PETITES MOLÉCULES DE L'ACTIVITÉ TRP-P8
专利权人:
Dendreon Pharmaceuticals; Inc.
发明人:
申请号:
EP08852382.4
公开号:
EP2268273B1
申请日:
2008.11.17
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Provided are small-molecule Trp-p8 modulators, including Trp-p8 agonists and Trp-p8 antagonists, and compositions comprising small-molecule Trp-p8 agonists as well as methods for identifying and characterizing novel small-molecule Trp-p8 modulators and methods for decreasing viability and/or inhibiting growth of Trp-p8 expressing cells, methods for activating Trp-p8-mediated cation influx, methods for stimulating apoptosis and/or necrosis, and related methods for the treatment of diseases, including cancers such as lung, breast, colon, and/or prostate cancers as well as other diseases, such as benign prostatic hyperplasia, that are associated with Trp-p8 expression.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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