Syringes and methods of using are described which protect materials within the syringe barrel cavity from contaminants and photo-chemical degradation. A syringe is provided having an inspection window for viewing medications or other materials within the cavity of a syringe barrel. The syringe barrel and other syringe components may be colored, opaque, darkened, amber, tinted or the syringe barrel may have applied thereto polarizing filters or materials having light polarizing properties can be used to manufacture the syringe barrel and other syringe components of the syringe to cancel particular components of light.