MARK A. REED,THOMAS K. WOOD,SCOTT C. BANFIELD,CHRISTOPHER J. BARDEN,ARUN YADAV,ERHU LU,FAN WU
申请号:
PT15755943
公开号:
PT3110812T
申请日:
2015.02.27
申请国别(地区):
PT
年份:
2019
代理人:
摘要:
in which R11 is e.g., 4-(pyrrolidin-1-yl)piperidin-1-yl, N-methyl-3-(pyrrolidin-1-yl)propan-1-amino, N1,N1,N3-trimethylpropane-1,3-diamino, N,N-dimethylpiperidin-4-amino, 3-(pyrrolidin-1-ylmethyl)azetidin-1-yl, 3-(pyrrolidin-1-ylmethanon)azetidin-1-yl, or 3-(morpholin-1-ylmethyl)azetidin-1-yl; R13 is, e.g., phenyl optionally substituted with one or more substituents; and R12 and R14 are each independently hydrogen or alkyl. Methods of treatment are also provided.