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N1-PYRAZOLOSPIROKETONE ACETYL-COA CARBOXYLASE INHIBITORS
专利权人:
PFIZER INC.
发明人:
BAGLEY, SCOTT, WILLIAM,GRIFFITH, DAVID, ANDREW,KUNG, DANIEL, WEI-SHUNG
申请号:
NZ59981510
公开号:
NZ599815A
申请日:
2010.10.29
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
599815 The disclosure provides a compound of Formula (I) or a pharmaceutically acceptable salt of the compound, wherein R1, R2, R3 and R4 are as described herein pharmaceutical compositions thereof and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl- CoA carboxylase enzyme(s) in an animal. Examples of compounds of formula (I) are: 1-isopropyl-1-(1 H-pyrrolo[3,2-b]pyridine-6-carbonyl)-4,6-dihydrospiro[indazole-5,4-piperidin]-7(1H)-one and 1-isopropyl-1-(2-methyl-1 H-benzo[d]imidazole-6-carbonyl)-4,6-dihydrospiro[indazole-5,4-piperidin]-7(1H)-one.
来源网站:
中国工程科技知识中心
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