599815 The disclosure provides a compound of Formula (I) or a pharmaceutically acceptable salt of the compound, wherein R1, R2, R3 and R4 are as described herein pharmaceutical compositions thereof and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl- CoA carboxylase enzyme(s) in an animal. Examples of compounds of formula (I) are: 1-isopropyl-1-(1 H-pyrrolo[3,2-b]pyridine-6-carbonyl)-4,6-dihydrospiro[indazole-5,4-piperidin]-7(1H)-one and 1-isopropyl-1-(2-methyl-1 H-benzo[d]imidazole-6-carbonyl)-4,6-dihydrospiro[indazole-5,4-piperidin]-7(1H)-one.