Wan Chen,Tse Siang Kang,Manjunatha Ramachandra Kini
申请号：
US14901517
公开号：
US09745363B2
申请日:
2014.07.01
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention is directed to a composition comprising an (one or more) isolated peptide comprising a BF01 peptide, variants of a BF01 peptide and/or mutants of a BF01 peptide. In particular aspects, the composition is a pharmaceutical composition. The composition(s) can be used to inhibit thrombogenesis, selectively inhibit the intrinsic pathway of blood coagulation and selectively inhibit FX1 in an individual in need thereof comprising administering an effective amount of all or a biologically active portion of a BF01 peptide, one or more variants thereof and/or one or more mutants thereof.
