AKEEFE, HASSIBULLAH,BELLOTTI, MARC,BREWER, H. BRYAN, JR.,CONNER, ADAM PAUL,PERLMAN, TIMOTHY JON
申请号：
DK10185381
公开号：
DK2368565T3
申请日:
2004.03.08
申请国别(地区):
DK
年份:
2015
代理人:
摘要：
The present invention is directed to systems, apparatus and methods for enriching pre-beta HDL without substantially affecting LDL. These derivatives of HDL are particles with reduced lipid content, particularly reduced cholesterol content. These particles have the capacity to bind cholesterol and are administered to a patient to enhance cellular cholesterol efflux and reduce cholesterol levels in cells, tissues, organs, and blood vessels. The present method is useful for treating atherogenic vascular disease and may be combined with other therapies such as statins, inhibitors of cholesterol absorption, niacin, anti-inflammatories, exercise and dietary restriction.
