Klaas Daniel Kussendrager,Henricus Alphonsus Maria Van Den Biggelaar
申请号：
US13408359
公开号：
US08501236B2
申请日:
2012.02.29
申请国别(地区):
US
年份:
2013
代理人:
摘要：
A method for producing a tableting additive, which method comprises providing a spray dried tableting additive in particulate form which particles at leas partially consist of amorphous additive material and at least partially of crystalline additive material and crystallising the amorphous additive material by subjecting the particles for a short time and under agitation to a temperature between 30 and 100° C. at a relative humidity between 60 and 25%. More in particular, the relationship between relative humidity and temperature is defined by the formula: % relative humidity=218-47*Ln(T(° C.)), wherein T(° C.) is the temperature to which the particles are subjected.
