BAN IVAN,WACHSMANN STEFAN,GERLING KLAUS-GUENTER,MUELLER HANS-JORG
申请号：
NO20052286
公开号：
NO332770B1
申请日:
2005.05.10
申请国别(地区):
NO
年份:
2013
代理人:
摘要：
Procedure for obtaining an extract containing the natural mixture of conjugated equine estrogens by Liquid liquid extraction of the mixture of conjugated equine estrogens, with the mixture obtained in non conjugated lipophilic compounds of the impoverished group includes Non conjugated flavonoids, isoflavonoids (norisoprenoides (no, no,Unconjugated steroids, in particular androstrano pregnane steroids and unconjugated Compounds, and comparable.Claim 1: procedure for obtaining a natural mixture of conjugated equine estrogens, wherein the mixture obtained is impoverished in non conjugated lipophilic compounds of the group that includes non conjugated flavonoids, isoflavonoids unconjugated, norisoprenoides Unconjugated, unconjugated steroids, in particular adrostano and pregnane steroids,Comparable and unconjugated Compounds, and because the procedure is Distinguished because: a) an aqueous Phase starting, Chosen of the Group comprising: (i) an aqueous solution of a natural mixture of conjugated oestrogens from Mare's urine Prenadas already impoverished substances co Nstitutivas phenol in urine(ii) an aqueous Concentrate of a natural mixture of conjugated oestrogens from Mare's urine Prenadas Precedent already impoverished constituent phenolic substances in the urine, (iii) a Concentrated Liquid of urine, and (iv) a Concentrated urine by prepurificado eventually FiltrationUndergoes a Liquid liquid extraction with a sufficient quantity of extraction agent which is a Water miscible Organic Solvent not or hardly miscible with her, suitable for extraction of non conjugated lipophilic compounds of the Group referred to above and below The separation of the aqueous Phase, and, eventually, b)With the obtained aqueous Phase repeats the procedure and Stage (a), (c) obtained an aqueous Phase containing the natural mixture of conjugated oestrogens and, eventually, this phase is concentrated.Det beskrives en fremgangsmåte for utvirming av en ekstiakt irmeholdende den naturlige bla
