David G. Hangauer, Jr.;Jonathon Salsbury;Grant J. Palmer;Daniel Coughlin;David G. Hangauer; Jr.;Jonathan Gale;Debasis Patra;Paul K. Isbester;Jeremy A. Cody
发明人:
David G. Hangauer, Jr.,Daniel Coughlin,Jonathan Gale,Jeremy A. Cody,Debasis Patra,Grant J. Palmer,Paul K. Isbester,Jonathon Salsbury
申请号:
US13094667
公开号:
US08293739B2
申请日:
2011.04.26
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to compositions comprising 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide and its mesylate and dihydrochloride salts. More specifically, the invention provides an efficient process for the synthesis of 2-(5-(4-(2-morpholinoethoxy) phenyl)pyridin-2-yl)-N-benzylacetamide and its mesylate and dihydrochloride salts and methods for modulating one or more components of a kinase cascade using the compositions of the invention.