COUGHLIN DANIEL,ISBESTER PAUL K,HANGAUER DAVID G JR,CODY JEREMY A,GALE JONATHAN,PALMER GRANT J,SALSBURY JONATHAN,PATRA DEBASIS
申请号:
IN4007/KOLNP/2009
公开号:
IN280315B
申请日:
2009.11.19
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The invention relates to compositions comprising 2-(5-(4-(2- mor- pholinoethoxy)phenyl)pyτidin-2-yl)—V-ben- zylacetamide and its mesylate and dihydrochloride salts. More specifically, the invention provides an efficient process for the synthesis of 2-(5-<4-(2-morpholi- noethoxy)phenyl)pyridin-2-yl)-ΛΛbenzylac- etainide and its mesylate and dihydrochloride salts and methods for modulating one or more components of a kinase cascade using the compositions of the invention.