An intravenous catheter inserter device (10) comprising a catheter inserter body (20) in which is slidably housed a septum activator (40), a catheter threader (60), and a needle hub (70). Some embodiments further include a safety bar (270) that is configured to assist in coordinating the movement of the various components of the device during a catheterization procedure. In general, the septum activator provides a pathway through a septum (120) of a Luer adapter (100). The Luer adapter comprises a wedge seal (130) that is configured to receive a base portion of a catheter that is inserted into the Luer adapter by the catheter threader. The final configuration provides an integrated unit that is attached to the patient and in fluid communication with patient's vascular system.
