LEVINE, BRUCE, L.,KALOS, MICHAEL, D.,JUNE, CARL, H.
申请号:
EP13816739
公开号:
EP2872184A4
申请日:
2013.07.12
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention provides compositions and methods for inducing tolerance in a human. The invention includes administering a genetically modified T cell expressing a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain.