Disclosed herein are dermatological formulations comprising low-impurity TOFA prodrug 2-(2-ethoxy-2-oxoethyl)(methyl)amino-2- oxoethyl 5-(tetradecyloxy)furan-2-carboxylate represented by Formula (Ia) and pharmaceutical use thereof:本文揭示包含由式(Ia)表示之低雜質TOFA前藥2-(2-乙氧基-2-氧代乙基)(甲基)胺基-2-氧代乙基5-(十四烷氧基)呋喃-2-羧酸酯之皮膚調配物及其醫藥用途:。無