Viranga Tillekeratne,Richard A. Hudson,Mamoun Alhamadsheh
申请号:
US12532829
公开号:
US08435983B2
申请日:
2008.03.20
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A method for synthesizing anti-leukemic epothilone analogues includes rigidifying a region between the macrolactone ring and the aromatic side-chain. The anti-leukemic compositions are non-naturally occurring epothilone analogue that are rigidified between the macrolactone ring and the aromatic side-chain.