ZENG, QINGPING,WADE, WARREN S.,PATTERSON, JOHN BRUCE
申请号:
EP10828948
公开号:
EP2496230A4
申请日:
2010.11.01
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The invention provides compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.