For variable use and simple construction of an instrument guide, particularly for inserting a puncture needle into patients, wherein the instrument guide (1) has a main body (2), which is mounted pivotably in a plurality of axes preferably on two adjusting arms (3, 4), according to the invention the instrument guide (1) has two or more guide cheeks (5), which are centrally adjustable and coupled to one another. This ensures that, when changing between instruments or needles of different thicknesses, the centre of the needle channel remains precisely on the target or central axis (6a).
