Michel Demeule;Jean-Paul Castaigne;Anthony Regina;Catherine Gagnon;Christian Che;Richard Béliveau;Reinhard Gabathuler
发明人:
Michel Demeule,Christian Che,Anthony Regina,Richard Béliveau,Catherine Gagnon,Jean-Paul Castaigne,Reinhard Gabathuler
申请号:
US12988269
公开号:
US08710013B2
申请日:
2009.04.20
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Pharmaceutical compositions useful for hydrophobic agents paclitaxel, paclitaxel analogs and conjugates thereof (e g ANG1005) which do not contain Cremophor™ The compositions further comprise an optional tonicity agent, a buffering agent a bulking agent and a solubilizing agent which is not Cremophor™ Methods of preparing said compositions and of said compositions in the treatment of cancer are also included.