A filtration membrane holder includes a top plate and a bottom plate. The top plate includes crossbars of a first "*" shape and a matching part at the side of a periphery of the top plate. The bottom plate is a cavity structure and includes crossbars of a second "*" shape and a matching cavity at the side of a periphery of the bottom plate. When the top plate and the bottom plate are assembled, the matching part of the top plate is correspondingly combined with the matching cavity of the bottom plate to deposit the top plate within the cavity structure of the bottom plate and to make the crossbars of the first "*" shape and the ones of second "*" shape be assembled tightly. The area and strength of the filtration membrane holder may support a filtrate membrane and prevent it from curving and shedding, as well as pass blood plasma without resistance.一種過濾膜支架，由上蓋板及底座板所構成，其中上蓋板具有第一米字形橫桿，且於上蓋板的周圍側邊上具有對合部，而底座板為凹槽結構且具有第二米字形橫桿，在底座板的周圍側邊上具有對合槽，當上蓋板與底座板結合時，利用上蓋板的對合部與底座板的對合槽相對應並結合，使得上蓋板可容置於底座板的凹槽結構內，且上蓋板的第一米字形橫桿與底座板的第二米字形橫桿相對應的緊密結合，藉由過濾膜支架的面積和硬度足以支撐過濾膜不會翻捲脫落，不會產生阻力而影響血漿的流通。
