Provided is a method for manufacturing an interdental cleaning device (1) including a base portion (10) having a handle portion (11) and a core portion (12); and a soft portion (20) having a cleaning soft portion (21), a non-slip portion (22), and connecting portions (23) extending from two sites of the non-slip portion (22) and being connected to the cleaning soft portion (21). The method includes causing a second gate (49) of second molds (40) and (41) for molding the soft portion (20) to open at a position substantially equally distant from positions of two communicating openings (48a) of a non-slip molding space (47) for molding the non-slip portion (22), the two communicating openings (48a) communicating with connecting portion molding spaces (48) for molding the connecting portions (23); and charging the elastomeric material from the second gate (49) into a second molding space (42) for molding the soft portion (20) to fill the molding space (42).