BERGSAGEL, Peter;MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH;STEWART, Alexander Keith;FONSECA, Rafael;BRAGGIO, Esteban
发明人:
STEWART, Alexander Keith,BERGSAGEL, Peter,FONSECA, Rafael,BRAGGIO, Esteban
申请号：
USUS2012/028285
公开号：
WO2012/125405A9
申请日:
2012.03.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
This document provides methods and materials related to assessing responsiveness to lenalidomide, thalidomide, and/or other IMiDs (structural and functional analogues of thalidomide that represent a promising new class of immunomodulators). For example, methods and materials for using CRBN levels to determine whether or not cancer cells (e.g., multiple myeloma cells) are susceptible to lenalidomide, thalidomide, and/or other IMiDs are provided.
