Disclosed herein is a light source device for fluorescence diagnosis and photodynamic therapy comprising: a plurality of light source means having a wavelength range different from each other and providing selected light a light path coupling means coupling light emitted from the light source means to the incident direction of a light guide a filtering means selectively transmitting the emitted light based on the wavelength and a switching device that is directed to an opening/closing means, established at a long distance to be controlled by a remote control device and selecting the kinds of light sources of the light source means to change the modes of the light. Accordingly, the device simplifies the configuration by excluding elements causing errors in the process of fluorescence diagnosis in the diagnostic region. Moreover, the light source device for fluorescence diagnosis and photodynamic therapy couples the light emitted from a combined light source to provide a sufficient light strength in the visible light region, thus improving the illumination quality to increase the accuracy of the diagnosis and further improving the therapeutic efficiency.
