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Trifluorometylowane alkohole jako modulatory ROR-gamma-t
专利权人:
Janssen Pharmaceutica NV
发明人:
VENKATESAN, HARIHARAN,TANIS, VIRGINIA,KINZEL, OLAF,GEGE, CHRISTIAN,STEENECK, CHRISTOPH,KLEYMANN, GERALD,HOFFMANN, THOMAS,GOLDBERG, STEVEN,FOURIE, ANNE M.,XUE, XIAOHUA
申请号:
PL15802227
公开号:
PL3212643T3
申请日:
2015.10.30
申请国别(地区):
PL
年份:
2019
代理人:
摘要:
The present invention comprises compounds of Formula I. wherein: X, A 1 , A 2 , A 3 , A 4 , R 1 , R 2 , and R 3 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORyt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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