VÉHICULES D'ADMINISTRATION INTRACELLULAIRE BISPÉCIFIQUE

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专利权人:

UNIVERSITY OF WASHINGTON;PHASERX, INC.

发明人:

STAYTON, PATRICK, S.,HOFFMAN, ALLAN, S.,CONVERTINE, ANTHONY,DUVALL, CRAIG, L.,OVERELL, ROBERT,JOHNSON, PAUL

申请号：

EP09825146

公开号：

EP2352522A4

申请日:

2009.05.13

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

A composition for delivering an agent to a cell, comprising a bispecific affinity reagent and a pH-responsive, membrane destabilizing polymer. The bispecific affinity reagent may include a first affinity reagent covalently linked to a second affinity reagent, wherein the first affinity reagent binds to a molecule on the surface of a cell, and the second affinity reagent binds to an intracellular target.

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