PROBLEM TO BE SOLVED: To provide a shrinking agent for keratinocyte which acts on a keratinocyte and can convert pores to be inconspicuous.SOLUTION: The shrinking agent for a keratinocyte comprises a compound represented by the following general formula (1) or its salts: R-X (1), wherein R shows an 8-20C alkyl group in which at least one hydrogen atom is substituted by an -OPO3H2 group, and X represents an -OPO3H2 group or a -COOH group.COPYRIGHT: (C)2008,JPO&INPIT【課題】ケラチノサイトに作用し、毛穴を目立たなくさせることのできるケラチノサイト収縮剤を提供すること。【解決手段】下記一般式(1)で表わされる化合物又はその塩R-X (1)〔式中、Rは少なくとも1つの水素原子が-OPO3H2基に置換した炭素数8~20のアルキル基を示し、Xは-OPO3H2基又は-COOH基を示す。〕を含有するケラチノサイト収縮剤。【選択図】なし