LAWRENCE T. BONI,BRIAN S. MILLER,VLADIMIR MALININ,XINGONG LI,LAWRENCE T. BONI,BRIAN S. MILLER,VLADIMIR MALININ,XINGONG LI
申请号:
IN353/DELNP/2008
公开号:
IN276035B
申请日:
2008.01.14
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
Provided are lipid antiinfective formulations substantially free of antonic lipids with a lipid to antiinfective ratio is about 1 :1 to about 4:1, and a mean average diameter of less than about 1 urn. Also provided is a method of preparing a lipid antiinfective formulation comprising an infusion process. Also provided are lipid antiinfective formulations wherein the lipid to drug ratio is about 1 : 1 or less, about 0.75:1 or less, or about O.SO: 1 or less prepared by an in line fusion process. The present invention also relates to a method of treating a patient with a pulmonary infection comprising administering to the patient a therapeutical]/ effective amount of a lipid antiinfective formulation of the present invention. The present invention also relates to a method of treating a patient for cystic fibrosis comprising administering to the patient a therapeudcally effective amount of a lipid antiinfective formulation of the present invention.