The product according to the present invention is produced in a production process using the mycelium of a mushroom such as Ganoderma lucidum. The production process encourages the growing mycelium to export bioactive compounds such as beta glucans into the surrounding liquid. Thus, the beta glucan is soluble and easily absorbed. More importantly, the production process allows the beta glucan to retain its triple helix structure which is required for maintain a very high bioactive efficacy. The beta glucans from Ganoderma lucidum can be used in a cream for treatment of psoriasis.