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COMPOSES UTILES POUR LE TRAITEMENT DU CANCER
专利权人:
ABIVAX SA;INSTITUT CURIE;UNIVERSITE DE MONTPELLIER;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人:
ROUX, PIERRE,MAHUTEAU, FLORENCE,NAJMAN, ROMAIN,TAZI, JAMAL,GADEA, GILLES,SCHERRER, DIDIER,BROCK, CARSTEN,CAHUZAC, NATHALIE
申请号:
CA2965791
公开号:
CA2965791C
申请日:
2010.06.14
申请国别(地区):
CA
年份:
2020
代理人:
摘要:
The invention relates to compounds of formula (Iq):(see formula Iq)wherein:R independently represents hydrogen, halogen or a group being ¨CN, hydroxyl,¨COOR1, (C1-C3)fluoroalkyl, (C1-C3)fluoroalkoxy, ¨NO2, ¨NR1R2, (C1-C4)alkoxy,phenoxyor (C1-C3)alkyl group, said alkyl being optionally mono-substituted by ahydroxyl,R1 and R2 are independently hydrogen or a (C1-C3)alkyl,n is 1, 2 or 3,n' is 1 or 2,R' is hydrogen, halogen or a group being (C1-C3)alkyl, hydroxyl, ¨COOR1, ¨NO2, ¨NR1R2, morpholinyl or morpholino, N-methylpiperazinyl, (C1-C3)fluoroalkyl,(C1-C4)alkoxy or ¨CN, andR" is hydrogen or (C1-C4)alkyl,or any one of its pharmaceutically acceptable salts.These compounds are useful for preventing, inhibiting or treating cancer.The invention also relates to pharmaceutical compositions comprising at leastone of thecompounds or salts thereof and one or more pharmaceutical excipients.
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