James SISSONS,Cameron BRANDT,Alexandra CROFT,Allen EBENS,Haley PEPER,Dean Y. TOY,Brian BELMONT,Stephen GOLDFLESS,Yue JIANG,Timothy JOHNSTONE,David KOPPSTEIN,Hieu NGUYEN,Blythe SATHER,Sonia TIMBERLAKE
申请号:
US16338452
公开号:
US20190225692A1
申请日:
2017.10.03
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.