JUNG, SUNG YOUB,郑圣烨,鄭聖燁,JANG, MYUNG HYUN,张明贤,張明賢,SHEN, LING AI,申玲爱,申玲愛,PARK, YOUNG KYUNG,朴荣敬,朴榮敬,PARK, YOUNG JIN,朴永振,KWON, SE CHANG,权世昌,權世昌
申请号：
TW101120633
公开号：
TWI619724B
申请日:
2012.06.08
申请国别(地区):
TW
年份:
2018
代理人:
摘要：
The present invention relates to a novel peptide showing more excellent activities on a glucagon like peptide-1 receptor and a glucagon receptor than native oxyntomodulin, and a composition for the prevention or treatment of obesity comprising the peptide as an active ingredient. Unlike native oxyntomodulin, the novel peptide of the present invention reduces food intake, suppresses gastric emptying, and facilitates lipolysis with reduced side-effects, and also shows excellent receptor-activating effects. Thus, it can be widely used in the treatment of obesity with safety and efficacy.本發明係有關一種對類升糖素肽-1受體與升糖素受體之活性比天然調酸素優異之新穎之肽，以及有關一種包含該肽作為活性成份之用於預防或治療肥胖之組成物。不同於天然調酸素，本發明之新穎肽減少食物攝取、抑制胃排空與促進脂肪分解，且具有減少之副作用，此外亦展現優異之受體活化效用。因此其具有廣泛用於治療肥胖之安全性與效力。
