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Sorbent Processing of Dialysate to Increase Solute Removal During Hemodialysis
专利权人:
The Board of Trustees of the Leland Stanford Junior University
发明人:
Timothy W. Meyer
申请号:
US16795954
公开号:
US20200289734A1
申请日:
2020.02.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A hemodialysis device and method are provided in which a hemodialyzer is designed for blood to flow past a semipermeable membrane and for a dialysate to flow in the opposite direction on the other side of the semipermeable membrane where uremic solutes are capable of diffusing from the blood into the dialysate passing the semipermeable membrane, and further designed in which a sorbent incorporated in a dialysate path as the dialysate passes the semipermeable membrane. The sorbent binds to non-urea uremic solutes and in particular to non-urea uremic solutes that bind to plasma proteins. In addition, the sorbent binds urea and inorganic ions much less effectively than non-urea uremic solutes and in particular to non-urea uremic solutes that bind to plasma proteins.
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