A storage and mixing device for PMMA bone cements having a cylindrical interior of the cartridge that is delimited on a front side by a cartridge head with a closed delivery opening, a plunger which is arranged to be axially movable in the cylindrical interior of the cartridge and which is spaced from the cartridge head. The plunger circumferentially rests against the inner wall of the interior, so that the plunger divides the interior of the cartridge into two sections in a gas-tight manner, a powdery first parent component of the bone cement, which is contained in the interior between the plunger and the cartridge head, a feed-through which is arranged in the cartridge head or in the cylinder barrel of the cartridge between the plunger and the cartridge head, wherein the feed-through is connected to a fluid line in which a monomer liquid as a second parent component of the bone cement is contained or into which a monomer liquid is fillable or introducible. A filter is arrangeable in the cartridge head, in the feed-through and/or in the fluid line, wherein the filter is permeable to the monomer liquid and impermeable to the first parent component, wherein the plunger is spaced from a back side of the cylindrical interior, located opposite the front side, to an extent that, by moving the plunger in the direction of the back side, a reduced pressure is producible in the interior of the cartridge between the plunger and the cartridge head, wherein the reduced pressure is able to suck the monomer liquid out of the fluid line into the interior of the cartridge.
