JEON, Hong Ryeol,全泓烈,KWON, DoWoo,权度又,權度又,LEE, BongSang,李凤相,李鳳相,PARK, SuJun,朴秀晙,CHA, BongGeun,车奉根,車奉根,KIM, JunKi,金准基,HAN, Jiyeong,韩知姈,韓知姈,KIL, Myeongcheol,吉明哲
申请号：
MOJ003842
公开号：
MOJ003842B
申请日:
2019.09.11
申请国别(地区):
MO
年份:
2019
代理人:
摘要：
The film preparation and preparation method thereof that the present invention relates to a kind of to be administered orally with what, the film preparation includes Tadalafei free alkali. The present invention provides a kind of film, by adding a small amount of dispersion stabilizer, the dispersion stabilization of Tadalafei free alkali reaches maximum in the film, the unique fragrance or smell not being likely to occur when using other dispersion stabilizers known in the art, and the caking phenomenon of Tadalafei free alkali particle will occur for minimum possibility, and can be substantially reduced the bubbles volume generated in process of production.本發明涉及一種用於口服給藥的膜製劑及其製備方法，所述膜製劑包括他達拉非游離碱。本發明提供一種膜，通過添加少量分散穩定劑，在該膜中他達拉非游離碱的分散穩定性達到最大，沒有當使用本領域已知的其它分散穩定劑時可能出現的獨特的芳香或氣味，且極小可能將會發生他達拉非游離碱顆粒的結塊現象，並可以明顯降低在生産過程中産生的氣泡量。
