The present invention provides an organic silicon-modified acrylic polyester potassium salt prepared from acrylic acid or its esters, propylene organic silicon, potassium persulfate, isopropyl alcohol, potassium hydroxide and deionized water. The mass ratio of the acrylic acid or its esters, propylene organic silicon, potassium persulfate, isopropyl alcohol, potassium hydroxide and deionized water is 15.0 to 20.0: 0.7 to 2.0: 0.3 to 1.0: 6.0 to 10.0: 8.0 to 15.0: 52.0 to 70.0. The invention also provides a preparation method of the aforementioned organic silicon-modified acrylic polyester potassium salt. The present invention further provides the use of preparation, treatment, a drug or health care products for cancer prevention using the above organic silicon-modified acrylic polyester potassium salt. The organic silicon-modified acrylic polyester potassium salt of the present invention is capable of controlling heavy metal toxicity, thereby rapidly preventing cancer from occurring, moreover, it has health care functions.本發明提供了一種有機矽改性丙烯酸聚酯鉀鹽,由丙烯酸或其酯類、丙烯有機矽、過硫酸鉀、異丙醇、氫氧化鉀和去離子水製備而成,所述的丙烯酸或其酯類、丙烯有機矽、過硫酸鉀、異丙醇、氫氧化鉀和去離子水的質量比為15.0~20.0:0.7~2.0:0.3~1.0:6.0~10.0:8.0~15.0:52.0~70.0。本發明還提供了上述的一種有機矽改性丙烯酸聚酯鉀鹽的製備方法。本發明還提供了上述的有機矽改性丙烯酸聚酯鉀鹽在製備治療或者預防癌症的藥物或者保健品中的應用。本發明的有機矽改性丙烯酸聚酯鉀鹽可以控制重金屬毒,因而可以迅速的防治癌症,並且具有保健的作用。