PROBLEM TO BE SOLVED: To provide a biological feed which is highly safe against the environment and fish larvae, inexpensive, excellent in sustainability, and which has an immunological activation that enhances the body's defense ability against pathogenic bacterial infections, viral infections and parasitic diseases. provide. A feed containing a lactoferrin-trivalent iron ion complex or an ascorbic acid-trivalent iron ion complex as a single complex or a complex complex is fed to a biological feed of fish and shellfish for immunoreactivity. Biological feed with an activator added to the body. [Selection diagram] None【課題】環境や魚類仔稚に対して安全性が高く、安価で、持続性に優れ、病原菌感染症、ウイルス性感染症、寄生虫症に対する生体防御能を高める免疫活性賦活を有する生物飼料を提供する。【解決手段】ラクトフェリン―3価鉄イオンとの錯体、アスコルビン酸―3価鉄イオンとの錯体を単一錯体か複合錯体で含有させた飼料を、魚介類の生物飼料に摂餌させ、免疫活性賦活剤を体内に附加させた生物飼料。【選択図】なし