經唑取代之吡啶化合物农业专利-农业学术服务平台

发明人:: TANAKA, HIROAKI,田中宏明,KAWAMURA, MADOKA,川村円,HAMADA, MAKOTO,滨田诚,濱田誠,KOBASHI, YOHEI,小桥阳平,小橋陽平,ITO, YUJI,伊藤勇次,SUZUKI, KAZUAKI,铃木一瑛,鈴木一瑛,BOHNO, AYAKO,坊野绫子,坊野綾子,FUNAYAMA, KOSUKE,舟山浩介

摘要：: The present invention provides a compound represented by formula [I], the compound exhibiting the effect of inhibiting an enzyme that produces 20-HETE, or a pharmaceutically acceptable salt thereof. (In formula [I], the structure represented by formula [II] indicates any one of the structures represented by formula group [III]； R1, R2, R3, and R4 independently indicate a hydrogen atom, a fluorine atom, a methyl group or the like； and R5 indicates any one of the structures represented by formula group [IV]).本發明提供具有阻礙產生20-HETE之酵素的作用之下述式[I]表示之化合物或其製藥學上容許之鹽。(上述式[I]中，下述式[II]表示之構造，係表示下述式群[III]表示之構造之任一者；R1、R2、R3，及R4係獨立地表示氫原子、氟原子、甲基等，R5表示下述式群[IV]表示之構造之任一者：，，，。