ZHONGSHAN OPHTHALMIC CENTER, SUN YAT-SEN UNIVERSITY; LTD.;GUANGZHOU HUI BO RUI BIOLOGICAL PHARMACEUTICAL TECHNOLOGY CO., LTD.;GUANGZHOU HUI BO RUI BIOLOGICAL PHARMACEUTICAL TECHNOLOGY CO.
发明人:
HOU, RUI,LUO, HONGRONG
申请号:
EP14782609
公开号:
EP2985283A4
申请日:
2014.04.09
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
Disclosed are an anti-abnormal proliferation of angiogenesis compound represented by formula I, use and intermediate thereof. The compound has good effect against abnormal proliferation of angiogenesis, and the activity of the compound is produced by inhibiting VEGFR2. The compound can be used for treating diseases, such as wet macular degeneration, inflammation, malignant tumor and the like, caused by abnormity of angiogenesis and protein kinases such as VEGFR2, FGFR2 and the like.