Zhongshan Ophthalmic Center, Sun Yat-Sen University;Zhongshan Ophthalmic Center; Sun Yat-Sen University;Guangzhou Kang Rui Biological Pharmaceutical Technology Co., Ltd.
发明人:
Hou, Rui,Luo, Hongrong
申请号:
AU2014252584
公开号:
AU2014252584A1
申请日:
2014.04.09
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
Disclosed are an anti-abnormal proliferation of angiogenesis compound represented by formula I, use and intermediate thereof. The compound has good effect against abnormal proliferation of angiogenesis, and the activity of the compound is produced by inhibiting VEGFR2. The compound can be used for treating diseases, such as wet macular degeneration, inflammation, malignant tumor and the like, caused by abnormity of angiogenesis and protein kinases such as VEGFR2, FGFR2 and the like.