Patrick Wai-Kwok SHUM;Gregory T. STOKLOSA;Thaddeus R. NIEDUZAK;Yong Mi CHOI-SLEDESKI;Gregory B. POLI;Zhicheng ZHAO
发明人:
Yong Mi CHOI-SLEDESKI,Thaddeus R. NIEDUZAK,Gregory B. POLI,Patrick Wai-Kwok SHUM,Gregory T. STOKLOSA,Zhicheng ZHAO
申请号:
US13488541
公开号:
US20120245199A1
申请日:
2012.06.05
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates herein to compounds and compositions for the treatment and amelioration of inflammatory disease. Specifically the present invention relates to compounds that having a tryptase inhibition activity and the intermediates thereof, pharmaceutical compositions comprising such compounds, and a method of treating subjects suffering from a condition disease or disorder that can be ameliorated by the administration of an inhibitor of tryptase.