Yong- Mi CHOI-SLEDESKI;Patrick Wai-Kwok SHUM;Grzegory T. STOKLOSA;Guyan LIANG;Charles J. GARDNER;Gregory B. POLI;Zhicheng ZHAO
发明人:
Yong- Mi CHOI-SLEDESKI,Charles J. GARDNER,Guyan LIANG,Gregory B. POLI,Patrick Wai-Kwok SHUM,Grzegory T. STOKLOSA,Zhicheng ZHAO
申请号:
US13396111
公开号:
US20120142735A1
申请日:
2012.02.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention extends to a compound of formula I:or a pharmaceutically acceptable salt of said compound, or a pharmaceutical composition comprising the compound of formula I and a pharmaceutically acceptable carrier. The invention is also directed to the use of a compound of formula I as an inhibitor of tryptase and for treating a patient suffering from, or subject to, a physiological condition in need of amelioration by an inhibitor of tryptase. The invention further includes methods for the preparation of a compound of formula I.